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Agrisera表观遗传学相关抗体促销开始啦!

表观遗传学是指基于非基因序列改变所致基因表达水平变化。表观遗传的现象目前已知的包括DNA甲基化、基因组印记、母体效应、基因沉默、核仁显性、休眠转座子激活和RNA编辑等。

其中组蛋白(Histone)的修饰作用是表观遗传学研究的一个重要领域。Histone H3与H2A、H2B和H4一起参与真核细胞中染色质的结构。组蛋白H3通过承受几种不同类型的表观遗传修饰,参与并影响许多细胞进程,如转录激活/失活、染色体包装、DNA损伤/修复。这些修饰,包括甲基化、瓜氨化、乙酰基化、磷酸化、小泛素相关修饰化、泛素化及二磷酸腺苷核糖基化。主要发生在组蛋白H3的N末端尾区域上,这导致核小体结构重构成更容易接近的开放构象的转录复合物。在大多数物种中,组蛋白H3主要在赖氨酸9,14,18,23和56处乙酰化; 在赖氨酸4,9,27,36和79处甲基化; 并分别在ser10,ser28,Thr3和Thr11磷酸化。组蛋白修饰的深入研究能更好地了解细胞过程的表观遗传调控。


 

 

 

 

西美杰为您整理并推荐Agrisera公司经过验证的,高质量的组蛋白表观遗传修饰抗体,产品如下:

产品名称

货号

适用物种

产品详情

H3K18me1 | Histone H3 (monomethylated Lys18)

AS16 3181

详情

H3K27ac | Histone H3 acetylated lysine 27 (ChIP grade)

AS16 3195

拟南芥、人、小鼠、大鼠

详情

H3K27me3 | Histone H3, trimethylated lysine 27 (H3K27me3)

AS16 3193

拟南芥、人、杨树、玉米等

详情

H3K37me1 | Histone H3 (Monomethylated Lys37)

AS16 3186

详情

H3K4me3 | Histone H3, trimethylated lysine 4

AS16 3190

拟南芥、人

详情

H3K56me1 | Histone H3 (monomethylated Lys56)

AS16 3187

详情

H3K9ac | Histone H3, acetylated lysine 9

AS16 3198

拟南芥、人等

详情

H3K9me2 | Histone H3 dimethylated lysine 9

AS16 3194

人、番茄

详情

H3R2me1 | Histone H3 (monomethylated Arg2)

AS16 3167

秀丽隐杆线虫、人

详情

H3S10p | Histone H3 (p Ser10) (affinity purified)

AS16 3635

详情

注:产品名称命名方式以组蛋白名称开始,如H3;单一字母的氨基酸简称,如K代表赖氨酸,以及在蛋白质的位置;修饰的种类,Me即甲基化、P即磷酸化、Ac即乙酰化Ub即泛素化


为满足广大表观遗传学研究方向客户的需求,
西美杰联合专业抗体品牌Agrisera推出表观遗传学相关抗体促销活动!
活动内容如下:

活动时间:即日起至6月30日

活动对象仅限终端客户参加

促销规则:促销产品限时“7折”特惠

促销产品除上述小编列举的组蛋白表观遗传修饰抗体外,更有50多种表观遗传学相关抗体正在进行促销,请见以下促销产品清单

产品名称

产品货号

5-fC | 5-formylcytosine

AS16 3165

5-hmC | 5-hydroxymethylcytosine (monoclonal)

AS16 3164

5-hmC | 5-hydroxymethylcytosine (polyclonal)

AS16 3166

5-mC | 5-methylcystosine (monclonal antibody for MeDIP/IF)

AS16 3162

5-mC | 5-methylcystosine (monclonal)

AS16 3161

5-mC | 5-methylcystosine (monclonal, clone 33D3)

AS16 3163

Acetylated lysine (25 µl, clone 7F8)

AS10 707-25

Acetylated Lysine (polyclonal)

AS15 3018

Acetylated Lysine, ALP conjugated

AS15 3019

Acetylated Lysine, FITC conjugated

AS15 3020

H2A.XS139p | H2A.X phosphorylated serine 139

AS16 3199

H3 | Histone 3 core | (monoclonal)

AS16 3197

H3K18me1 | Histone H3 (monomethylated Lys18)

AS16 3181

H3K18me2 | Histone H3 (dimethylated Lys18)

AS16 3182

H3K18me3 | Histone H3 (trimethylated Lys18)

AS16 3183

H3K27ac | Histone H3 acetylated lysine 27 (ChIP grade)

AS16 3195

H3K27me3 | Histone H3, trimethylated lysine 27 (H3K27me3)

AS16 3193

H3K27me3S28p | Histone H3 (trimethylated Lys27, p Ser28)

AS16 3184

H3K36me3 | Histone H3 trimethylated lysine 36 (ChIP grade)

AS16 3196

H3K37me1 | Histone H3 (Monomethylated Lys37)

AS16 3186

H3K4me1T6p | Histone H3 (monomethylated Lys4, p Thr6)

AS16 3171

H3K4me3 | Histone H3, trimethylated lysine 4 (H3K4me3)

AS16 3190

H3K4me3 | Histone H3, trimethylated lysine 4 (H3K4me3) (10 µg)

AS16 3190-10

H3K4me3T6p | H3 (trimethylated Lys4, p Thr6)

AS16 3172

H3K56me1 | Histone H3 (monomethylated Lys56)

AS16 3187

H3K56me3 | Histone H3 (trimethylated Lys56)

AS16 3188

H3K9ac | Histone H3, acetylated lysine 9

AS16 3198

H3K9me2 | Histone H3 dimethylated lysine 9

AS16 3194

H3R17me2(asym) | Histone H3 (asym-dimethyl Arg17)

AS16 3180

H3R2me1 | Histone H3 (monomethylated Arg2)

AS16 3167

H3R2me2(sym)K4me2 | Histone H3 (sym-dimethylated Arg2, dimethyl Lys4)

AS16 3185

H3R8me2(asym) | Histone H3 (asym-dimethylated Arg8)

AS16 3177

H3R8me2(sym) | H3 Histone 3 (sym-dimethylated Arg8)

AS16 3178

H3S10p | Histone H3 (p Ser10) (affinity purified)

AS16 3635

H3S10p | Histone H3 (p Ser10) (affinity purified, 10 µl)

AS16 3635-10

H3S10p | Histone H3 (p Ser10) (serum)

AS16 3636

H3S10pT11p | Histone H3 (p Ser10, p Thr11)

AS16 3179

H3T3pK4ac | Histone H3 (ac Lys4, p Thr3)

AS16 3170

H3T3pK4me1 | Histone H3 (p Thr3, monomethylated Lys4)

AS16 3168

H3T3pK4me2 | Histone H3 (dimethylated Lys4, p Thr3)

AS16 3169

H3T6p |  Histone H3 (p Thr6)

AS16 3173

H3T6pK9me1 | Histone H3  methylated at Lys9 (K9)

AS16 3174

H3T6pK9me2 | Histone H3 (dimethylated Lys9, p Thr6)

AS16 3175

H3T6pK9me3 | Histone H3 (trimethylated Lys9, p Thr6)

AS16 3176

H4K16ac | Histone H4 (ac Lys16)

AS16 3189

m6A | N6-methyladenosine (monoclonal)

AS17 4120

m6A | N6-methyladenosine (polyclonal)

AS17 4121

Methylated Lysine

AS15 3021

Methylated Lysine, APC conjugated

AS15 3022

Methylated Lysine, FITC conjugated

AS15 3023

 

 

西美杰做为Agrisera中国区代理为广大客户提供经过验证的高质量抗体,优质的售前咨询服务以及良好的抗体售后支持。此外西美杰代理的Lifespan、Mybiosource一抗、检测试剂盒以及SeraCare(KPL)二抗、底物全方位助力于科学研究实验。


 

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